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proceedings to evaluate the use of patient-reported measures of HRQOL in MS. A variety of .. MSQOL may represent a barrier to its use in clinical practice. Permission to use the MSQoL instrument was requested from the original author of They translated the 18 specific items of the MSQoL into Portuguese. The MS quality of life 54 (MSQOL) is an MS-specific HRQOL inventory originally . MSQOL scale scores were assembled using the Likert method for .

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Comparison in a national sample. Since there was no need for changes in version 2, this was the final version of the MSQoL in Portuguese. Fo criteria for fit indexes in covariance structure analysis: Select your language of interest to view the total content in your interested language.

Translation of the Multiple Sclerosis Quality of Life Brazilian Version | OMICS International

A limitation of the study is that we did not extensively revise the instrument in passing to the short version: We added a filter question after the first Sexual Function item so that subsequent subscale items can be skipped if not pertinent—to thereby reduce the burden of compilation S2 Appendix and distinguish between missed and non-pertinent items.

Finally cognitive debriefing of the new instrument vs. Therefore, the researchers conducted a conceptual review on the idiomatic, semantic, and conceptual equivalence of item content of the final Portuguese version.

Internal consistency reliability for these scales ranged from 0. The models assume unidimensionality—that all items here HRQOL subscale assess the same single construct of interest—and also local independence—that items do not correlate with each other when the latent trait has been controlled for.

The MSQoL questionnaire was filled in by the patients with presence of physician who could assist in of eventual problems in understanding questions and technical way of filling the questionnaire.

Twelve patients were interviewed 5 men, age range 21—68 years, EDSS range 0—7. One third of patients with MS will need to use a wheelchair.


In the short questionnaire, for a pair of categories with a disordered threshold, we retained the category that best expressed the order of the Likert scale and eliminated the other. Our aim was to work with the original set of items and subscales, retaining those that had the best psychometric characteristics.

For each subscale, items are reported in measurement order more difficult at top ; are category thresholds. In this respect, the content validity was approved. In general, there are four main steps involved in a linguistic validation of an instrument: Longevity is bimodally distributed with many patients having normal longevity and some dying at a significantly younger age depending on disease aggressiveness, disability severity, infection, or suicide [ 45 ].

Validation and cross-cultural adaptation of the disease-specific questionnaire MSQOL in Serbian multiple sclerosis patients sample. Quality of life in multiple sclerosis: After this first analysis, in each sub-scale the worst fitting item was deleted and the PCM re-run. Satorra A, Bentler PM. Rasch analysis of the dimensional structure of the Hospital Anxiety and Depression Scale.

Methodological approaches to shortening composite measurement scales. Incidence and prevalence of multiple sclerosis in Olmsted country, Minnesota Have others, such as your family or friends, noticed that you have trouble with your memory or concentration? There were minor differences ho the two. Permission to use the MSQoL instrument was requested from the original author of this questionnaire who approved the translation into Brazilian Portuguese.

Development of a Short Version of MSQOL-54 Using Factor Analysis and Item Response Theory

If thresholds between two response categories are disordered, the response categories are not working as intended. None of the items was identified by the patient sample as being embarrassing. Rasch analysis of a new stroke-specific outcome scale: The disease mainly affects young adults; more often women 1.

The aim was to assess the acceptability of the short version in comparison to the original and discover whether any of the removed items was considered important domain coverageor any revised response category was considered msqlo or unclear. We aimed to preserve both the conceptual model uze the psychometric go of the original instrument [ 14 ]. Interview content was analysed informally. It is estimated, based on data from clinics health insurance funds than MS affects more than 3.


Development of a Short Version of MSQOL Using Factor Analysis and Item Response Theory

Received Mar 5; Accepted Apr Regarding the latter point, Catherine Acquadro reported that item 47 —the only MSQOL item with a different wording in men difficulty getting or keeping an erection and in women inadequate lubrication was difficult to understand for women personal communication, Uxe explain these results, the study conducted in Turkey suggested that this was due to the fact that people with MS may find sex -related items distressing, difficult to understand, or too private [ 12 ].

Confirmation of these findings in an independent sample second phase of the project is however needed. The longevity of patients with MS is about eight years less than that of a healthy person.

Missing data in our study are avoided due to additional explanations and support by presenting physician. Its internal consistency reliability measured by Cronbach alpha coefficient is hoe above the minimum requirement in case of all scales. Quality of life and multiple sclerosis: RESULTS Demographic and clinical characteristics of patients enrolled in the study gow presented in Table 1including type of treatment receiving at the moment of filing the questionnaire.

A health-related quality of life measure for multiple sclerosis. Lucia Foundation, Rome, Italy. The lowest internal consistency reliability is found on usr function scale 0.

The structure of self-reported health in chronic disease patients. Factor analysis in the development and refinement of clinical assessment instruments. The 54 items of this questionnaire is distributed into 12 usd scales and jse single items. Within a week of questionnaire completion, a psychologist ATexperienced at interviewing, conducted individual telephone interviews with patients—who had their completed questionnaires to hand—using a semi-structured interview guide.